This is in line with research by Nangia-Makker et al., which stated that the ethanol extract of Ocimum sanctum, which belongs to the same genus as Ocimum basilicum, can inhibit tumor growth and angiogenesis by affecting tumor cell proliferation, migration, morphogenesis, stromal apoptosis and induction of COX-2 [25]. This evidence concerns the gene PTGS2 and neoplasm.