CD4 and pancreatic adenocarcinoma: 14 For PAAD patients with frequent 9p21 loss (vs 9p21-WT tumours), we observed a remarkable decrease in the abundance of T cells, natural killer (NK) cells, myeloid dendritic cells, monocytic lineage, fibroblasts, endothelial cells, cytotoxic lymphocytes, CD4 T cells, and B lineage (Fig. S8B).