ALBI, albumin-bilirubin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CLD, chronic liver disease; CRP, C-reactive protein; CONUT, controlling nutritional status; CRP, C-reactive protein; γ-GTP, γ-glutamyl transpeptidase; IGF-1, insulin-like growth factor-1; LS, liver stiffness; TG, triglycerides. The gene discussed is IGF1; the disease is congenital secretory chloride diarrhea 1.