As revealed by autopsy, some severe COVID-19 vaccine injury syndromes that may be directly or indirectly caused by spike protein include sudden cardiac death, myocardial infarction, myocarditis, pericarditis, pulmonary embolism, vaccine-induced immune thrombotic thrombocytopenia, brain hemorrhage, multi-organ failure, respiratory failure, and cytokine storm [12,41]. The gene discussed is CHMP5; the disease is COVID-19.