To evaluate the capacity of TAG‐72/CD3ε FP T cells to lyse tumor cells, high (OVCAR‐3) or low (ME‐SOV) TAG‐72 expressing cells were co‐cultured with TAG‐72/CD3ε FP T cells, TAG‐72 CAR‐T cells or negative control effector T cells. The gene discussed is CD3E; the disease is neoplasm.