Both TAG‐72 CAR‐T cells and TAG‐72/CD3ε FP T cells displayed in vivo anti‐tumor activity as compared to the NT group, with TAG‐72 CAR‐T cells displaying a prolonged anti‐tumor response compared to TAG‐72/CD3ε FP T cells (Figure 4a,b). This evidence concerns the gene CD3E and neoplasm.