In our analysis, 3 of the 34 ICD-related genes were considerably linked to the prognosis of BLCA patients, including CALR, IFNB1, and IFNG. Following this, we developed a risk model utilizing these three IRGs to assess its efficacy in prognosticating patient outcomes in BLCA. The gene discussed is IFNB1; the disease is bladder transitional cell carcinoma.