CD147 overexpression in pancreatic cancer correlated with that of amino acid (AA) transporters, L-type AA transporter (LAT1, an mTOR mediated essential AA transporter), system ASC AA transporter-2 (ASCT2, a neutral AA and glutamine transporter), and the heavy chain of LAT1 (4F2c, known to interact with CD147-MCT complex as well as LAT1) (24, 45). This evidence concerns the gene BSG and pancreatic neoplasm.