γH2AX is a protein marker for G2/M phase-homologous recombination DSBs repair; in vitro and in vivo studies, induction of DSBs through treatment with radiations of cervical cancer SiHa and ME-180 cell lines resulted in CD147-dependent evasion of DDR and cell cycle rescue; exposure to 10-Gy of CD147+ SiHa and ME-180 had a rapid decrease of γH2AX within 1 and 6 hours of exposure respectively meanwhile CD147- cells had a rapid increase of γH2AX, reaching maximal values within 30 minutes of exposure and remained at maximal for 24 hours post-exposure. Here, BSG is linked to cervical cancer.