Prednisone can exert anti-inflammatory, anti-allergic, and immunosuppressive effects by binding to the cytoplasmic glucocorticoid receptor and can be used to treat various allergic diseases, bacterial infections, eczema, systemic lupus erythematosus, exfoliative dermatitis, etc. (16). This evidence concerns the gene NR3C1 and systemic lupus erythematosus.