Drastically, the combination of miR-99b-5p and Enz exerted a synergistic effect to further decrease the occupancies of mTOR (or mTOR/AR) on these genes in all the tested PCa cell lines, including the Enz-resistant CRPC and AA PCa (miR-99b-5p/Enz vs. miR-99b-5p and miR-99b-5p/Enz vs. Enz, Figure 6). The gene discussed is MTOR; the disease is posterior cortical atrophy.