Intriguingly, almost exclusive cytoplasmic mTOR and AR signals were detected in PCa cells under treatment of either miR-99b-5p, Enz, or miR-99b-5p/Enz combination (Figure 4A), suggesting both miR-99b-5p and Enz treatments block the nuclear translocation of AR and mTOR. This evidence concerns the gene AR and posterior cortical atrophy.