AR and posterior cortical atrophy: Taken together, nuclear AR/AR-V7, SMARCD1 and mTOR (i.e. active/phosphorylated forms of proteins) were enriched in androgen-independent AA PCa (MDA PCA 2b), and nuclear AR/AR-V7 and SMARCD1 were enriched in EA CRPC (22Rv1 and C4-2B), potentially explaining the aggressiveness of AA PCa and CRPC.