To understand the regulation of miR-99b-5p/mTOR/AR signaling, the cellular locations of AR, AR-V7, mTOR and SMARCD1 were explored in EA PCa (LNCaP, PC-3, DU-145, 22Rv1, and C4-2B) and AA PCa (MDA PCa 2b) cell lines. The gene discussed is AR; the disease is posterior cortical atrophy.