SOAT1 and leukemia: The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway consist of a group of receptors and transmembrane proteins that recognize specific cytokines, essential for healthy hematopoiesis (33); in contrast, dysregulation of the JAK/STAT signaling pathway provides a survival advantage to leukemia cells by transmitting anti-apoptotic and proliferative signals (34).