CXCL12 and neoplasm: In glioblastoma cancer models, inhibition of the b-galactoside-binding lectin, galectin-1 has shown to enhance expression of CXCL10, CXCL12 and CCL5 resulting in recruitment of Gr-1+/CD11b+/CCR2+ myeloid cells which promoted the recruitment of tumor-infiltrating NK cells (138).