The engineered cell lines, as well as tissue sections from both neoplastic (non-small cell lung cancer adenocarcinoma, high grade serous ovarian cancer and clear cell renal cell carcinoma) and normal tissue (kidney, salivary gland, lung, cervix, skeletal muscle and endometrium), were immunohistologically examined with an IVD approved FRα antibody, and the resulting H-scores calculated (Figure 3A). The gene discussed is FOLR1; the disease is ovarian serous adenocarcinoma.