Figure 1 reveals that, aside from IL-2 and IL-4, levels of all other cytokines were elevated in GC patients compared to healthy individuals. Specifically, the differences in IL-6, IL-10, and TNF-αwere statistically significant (p<0.0001, p<0.0001, p = 0.021, respectively). It is worth highlighting that every blood cell component ratio studied exhibited statistical differences between the two cohorts. In healthy individuals, both TLC and LMR were higher (p<0.0001, p<0.0001), while GC patients had elevated NLR and PLR (p = 0.0085, p = 0.0034) (Table S6). This evidence concerns the gene IL4 and gastric cancer.