CRYAB and myeloid sarcoma: This multifaceted role somewhat confounded the MS field and cast doubt on CRYAB’s role as an autoantigen in MS, however antibody responses to CRYAB were recently revisited in a large Swedish cohort and showed 27.6% of pwMS and 16.9% of controls to have IgG responses to CRYAB peptides with homology to EBNA1, and were associated with MS (OR=1.98) (69).