Although some studies have documented that Sema7a contributes to atherosclerosis by mediating endothelial dysfunction and promotes the growth and migration of oral tongue squamous carcinoma cells by regulating the course of EMT (21, 33), little is known about whether Sema7a is involved in AR in allergic asthma by promoting the process of EMT. Here, SEMA7A is linked to allergic asthma.