Mutations in the RAS oncogene or the P53 tumor suppressor gene result in the loss of normal healthy cellular growth control, progressing to neoplastic cell proliferation and cancer [15,16]. Besides, disruption of harmony between pro- and antioxidant mechanisms due to oxidative stress, reactive oxygen species, and chronic local inflammation caused due to ST may promote an ideal microenvironment promoting tumor [17]. The gene discussed is TP53; the disease is neoplasm.