In another study, Zhang et al. compared the effects of dietary supplementation of foxtail millet and rice on colorectal cancer; it was found that foxtail millet inhibited the phosphorylation of STAT3 and the related signaling pathway proteins involved in cell proliferation, survival and angiogenesis (mediated by the activation of gut receptors, i.e., aryl hydrocarbon receptor, or AHR, and G-protein-coupled receptors, or GPCRs). The gene discussed is AHR; the disease is colorectal cancer.