NOS3 and coronary artery disorder: The research supports the global link of CAD with the three frequent NOS3 gene polymorphisms: Glu298Asp, T786-C, and 4a/b VNTR. The results between various ancestral subgroups were quite enlightening. The Middle Eastern grouping exhibited the strongest correlation with both the examined NOS3 SNPs, Glu298Asp and 4b/a. However, among individuals of Asian descent, the highest risk for CAD is carried by T786-C and its minor allele.