Numerous risk factors have been identified for the onset of AKI, encompassing conditions like heart and pulmonary diseases, liver failure, sepsis, advanced age, preexisting renal disease, and various medications including angiotensin-converting enzyme inhibitors (ACEIs), vasopressors, aminoglycosides, and nonsteroidal anti-inflammatory drugs (NSAIDs) [5]. This evidence concerns the gene ACE and acute kidney injury.