Result of fully adjusted binary logistic regression showed PR+ and HER2+ were positively associated with lower risk BC-LuC after adjusting confounders (ORs = 0.84, 95% CI: 0.73–0.96, p = 0.011 and ORs = 0.83, 95% CI: 0.72–0.96, p = 0.012, respectively). This evidence concerns the gene PGR and breast cancer.