PLIN2 and fatty liver disease: Because perilipin 2 is known to promote lipid droplet accumulation via inhibiting lipolysis(Brasaemle et al., 1997; Imamura et al., 2002; Magnusson et al., 2006; Listenberger et al., 2007), it is possible that the change in lipid droplet phospholipid composition observed in ethanol-fed rats drives the development of hepatic steatosis through perilipin 2 recruitment.