CXCL2 and hepatocellular carcinoma: Some previous studies confirmed that overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma as CXCL2 expression was stably down-regulated in HCC patients, and its overexpression made cell cycle stagnated at G0/G1 phase, profoundly attenuated HCC cell proliferation and growth and induced apoptosis in vitro 25.