In addition, it was reported that SLC2A9 might be a novel tumor suppressor gene that induced apoptosis in HCC cells by inhibiting the expression of caspase 3, and high expression of SLC2A9 could effectively inhibit the proliferation of HCC cells 31, suggesting that SLC2A9 may have an important biological role in HCC. The gene discussed is CASP3; the disease is hepatocellular carcinoma.