And FMRP (Protein of FMR1) binds RIPK1 mRNA, suggesting that FMRP acts as a regulator of necroptosis pathway through the surveillance of RIPK1 mRNA metabolism in colorectal cancer (Zhuang et al., 2020; Di Grazia et al., 2021). The gene discussed is RIPK1; the disease is colorectal cancer.