The transcriptome profile of nevi samples appears to resemble that of the superficial spreading melanoma, where the stem cell-related genes erbb2 and erbb3 and the mesenchymal signatures sox9, twist1a, twist1b, and twist3 showed increased expression (Buac et al., 2009; Travnickova et al., 2019; Diener and Sommer, 2021). This evidence concerns the gene ERBB2 and melanoma.