Blocking the IL-1 pathway in two different experimental mouse models of KD, the LCWE- and the Candida albicans water-soluble fraction (CAWS), either pharmacologically or using knock-out mice, significantly decreases vasculitis severity (Lee et al., 2012; Lee et al., 2015; Anzai et al., 2020; Porritt et al., 2020). Here, IL1B is linked to vasculitis.