Transcriptome analysis of whole blood from KD patients as well as cardiovascular tissues collected from Lactobacillus casei cell wall extract (LCWE)-injected mice, an experimental mouse model mimicking KD vasculitis, showed increased expression of genes associated with IL-1β and the NLRP3 inflammasome pathway (Hoang et al., 2014; Lee et al., 2015; Wakita et al., 2016; Porritt et al., 2021). This evidence concerns the gene NLRP3 and vasculitis.