INO80 and cancer: INO80 complex, a member of the ATP-dependent chromatin remodeler family, is involved in multiple functions related to cancer stem cells and cancer progression, through both canonical and non-canonical INO80 complexes that directly modulate chromatin architecture and gene expression (Min et al., 2013; Wang et al., 2014a; Lafon et al., 2015; Runge et al., 2018).