THSD4 and TBC1D9 are two factors that drive TNBC, and their expression is also linked to the epithelial–mesenchymal transition (EMT), metastatic dissemination, and the plasticity of breast cancer cells (Cohen et al., 2014; Kothari et al., 2020; Miao et al., 2020; Kothari et al., 2021). This evidence concerns the gene TBC1D9 and breast cancer.