We also found that the leading SNP in the IL18RAP locus showed concordant effects on the risk between leprosy and asthma, whereas the leading SNPs in the novel locus chr12:57,665,085‐58,665,085 and the IL27 locus showed discordant effects on the risk between leprosy and rheumatoid arthritis, multiple sclerosis, IBD, CD, and UC (Table S11). This evidence concerns the gene IL18RAP and asthma.