The concordant or discordant effects of the leading SNPs in the loci (IL12B, IL18RAP, IL23R, TNFSF15, LACC1, METTL1, and IL27) were identified in the present study, which further highlighted the involvement of immune responses and the shared genetic fingerprint of infectious diseases and autoimmune/inflammatory diseases. Here, TNFSF15 is linked to infectious disease.