A limited number of protein coding transcripts (n = 10) were classified as upregulated already by 30 min after stimulation in both sexes (Fig. 1Aii), including those encoding for components of the NF-κB signaling pathway (NFKBIA, NFKBIZ), chemokines regulated by this pathway (CXCL2, CXCL3, IL6), and FAM167A, which was recently described as an activator of the noncanonical NF-κB pathway in chronic myeloid leukemia (43) (Supplemental Table III). Here, NFKB1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.