Furthermore, several typical meningioma locations have distinct related genomic markers (e.g., anterior skull base: SMO, AKT1E17K, TRAF7; central skull base: AKT1, KLF4, TRAF7, POLR2A, Convexity: NF-2, LOH chromosome 22, BAP1) [29]. The gene discussed is SMO; the disease is meningioma.