FAS and infection: Our previous study showed that enhanced hepatic NK cell death by NKG2D/NKG2D ligand and Fas/Fas ligand contributed to hepatocyte necrosis in an MHV-3-FHF mouse model, and depletion of NK cells at 24 h post MHV-3 infection via anti-ASGM-1 could improve survival in an MHV-3-FHF model [8].