According to the literature search, only one article showed that RETN and SELE polymorphisms were significantly associated with coronary artery disease, but the relationship between RETN and SELE polymorphisms and CKD was not reported (PMID: 24,699,314).Further studies are needed to explore the association between Retn and SELE polymorphisms and CKD-PEW. Here, SELE is linked to chronic kidney disease.