SLC5A2 and hypertensive disorder: In this retrospective study of metformin monotherapy treated Asian population, baseline HbA1c, HTN disease duration, cholesterol HDL, creatinine serum, eGFR, existing renal complications, and HTN medication class of calcium antagonists, angiotensin-II receptor and beta blockers were independently associated with HbA1c outcome and were predictive of treatment response for SU, DPP-4 and SGLT-2 add-on medications.