On average, significantly more M1 macrophages and cytotoxic CD8 + T-cells, along with enhanced activations of B-cells, Th1 cells, cytotoxic cells and NK CD56dim cells were seen, suggesting an active immune-infiltrated tumor microenvironment potentially driving better survival prognosis for the PANoptosis High cluster in SKCM73. This evidence concerns the gene CD8A and neoplasm.