CTNS and cystinosis: In this study, we used a ctns−/−[Tg(l-fabp:DBP:eGFP)] fish model for cystinosis that shows a 15% reduction (mean) in green fluorescence at 5 days post-fertilization as compared with the ctns+/+[Tg(l-fabp:DBP:eGFP)] larvae, indicative of an increase in DBP-GFP protein loss in the fish water (Supplementary Fig. S3d).