Instead, we demonstrated that PP treatment did not affect ELAVL3 nuclear-cytoplasmic shuttling, but disrupted the interaction of ELAVL3 and its downstream mRNA, herein MYCN and RICTOR, subsequently leading to a reduction in ELAVL3-induced neuroendocrine differentiation and concomitant suppression of tumor growth. This evidence concerns the gene ELAVL3 and neoplasm.