Likewise, the genomic region of chromosome 17q21.31 also contained multiple genes that were associated both with schizophrenia and with all 3 MRI metrics, including NSF, KANSL1, CRHR1, ARHGAP27, LRRC37A, CCDC43, FMNL1, SPPL2C, MAPT, PLEKHM1, STH, and LINC002210-CRHR1. This evidence concerns the gene SPPL2C and schizophrenia.