RAI1 and hereditary disease: These top genes can be categorized into three types, that are: (1) 32 overlapping genes involved in both inherited diseases and cancers, such as NF1 (relates to both Neurofibromatosis type 162 and Leukemia63), (2) 68 inherited diseases genes (e.g., RAI1 and NRXN1), and (3) 68 cancer genes (e.g., ATR and RAF1).