Similarly, the enhancer activity of h-FLT3 was supported by more robust H3K27ac ChIP-seq signals in MLL-r acute myeloid leukemia (AML) cells (MOLM13, MOLM14, and MV4;11 cells) as compared with non-MLL-r AML cells (IMSM2, HEL, K562, SET2, U937, and HL60 cells) and normal CD34+ cells (Fig. 2B)35–37. Here, FLT3 is linked to acute myeloid leukemia.