One study examined methylation of the FoxP3 gene across a Treg-cell-specific demethylated region, whose expression in an unmethylated form ensures that naïve T cells develop into Tregs, and found that prenatal racial and ethnic discrimination exposure predicted postnatal mood disorders only in individuals with higher than average levels of FoxP3 methylation (Sluiter et al., 2020). This evidence concerns the gene FOXP3 and mood disorder.