Interestingly, the prognostic value of KIF14 mRNA expression in HNSCC patients was significantly increased by simultaneous high mRNA expression of KIF14 and low mRNA expression of CA9. CA9 is highly related to hypoxia and high levels of CA9 might accelerate survival of cancer cells and negatively affect response to treatment. Here, KIF14 is linked to head and neck squamous cell carcinoma.