CASP1 and lung carcinoma: In addition to the agents described above, Ophiopogonin B (112), secoisolariciresinol diglucoside (SDG) (93), and taxol (113) were also reported to induce pyroptosis, thus restraining the progression of lung cancer, colorectal cancer, and nasopharyngeal cancer, respectively, through the caspase-1/GSDMD pathway.