ANGPT2 and uveitis: In the present study, we demonstrated three new findings concerning the role of Ang2 and VEGFA in the pathogenesis of ocular inflammation: (1) the high protein levels of Ang2 and VEGFA in vitreous samples of uveitis patients relative to controls, (2) the high expression of both Ang2 and VEGFA during the time course of the EAU mouse model relative to controls, and (3) the protective effects of dual Ang-2/VEGF-A inhibition in a preclinical mouse EAU study.