Subsequently, we performed gene intersection analysis to pinpoint six genes, namely HS3ST3B1, FMOD, CSPG4, ALDH1A1, CYP1B1, and ENO1, which demonstrated associations with BLCA prognosis and immune infiltration among the pool of EMT- and energy metabolism-related genes. Here, HS3ST3B1 is linked to bladder transitional cell carcinoma.