Notably, taking advantage of SmartSeq2, they further detected 20 highly conserved unannotated exons (e.g. Cabp2 exon 1B, Cacna1d exon 1B, and Coch exon 3B) in 12 deafness-related genes, and discovered five subtypes of Cabp2 in 12 OHCs by using nanopore single-cell full-length transcriptome sequencing technology, which may have important implications for revealing the genetic basis of deafness. This evidence concerns the gene COCH and deafness.