To test if fat body insulin signalling facilitates cachexia progression via TGF‐β signalling, we next activated insulin signalling via fat body expression of InRCA and simultaneously knocked down TGF‐β signalling via fat body expression of madRNAi (Fig 3L–O) in tumour bearing animals (QRasV12, scribRNAi). This evidence concerns the gene INS and neoplasm.