RXFP1 is responsible for encoding relaxin receptor 1, a G protein-coupled receptor that is widespread in multiple organs such as the heart, blood vessels, kidneys, and lungs.[11] The main function of relaxin receptor 1 is to regulate the biological activity of relaxin, such as lowering blood pressure, resisting inflammation, and preventing fibrosis.[12] The role of RXFP1 may be complex during asthma pathology. Here, RXFP1 is linked to asthma.