Afterward, 8 lactylation-associated genes (CRABP2, GATAD2A, MDC1, LAP3, SATB1, TMSB4X, CALML5, and WAS) and 8 CALML5-associated lncRNAs (MIRLET7BHG, AL162457.2, AL122010.1, MIR193BHG, AC244153.1, AL390760.1, AL133371.2, and CCDC18-AS1) were utilized for constructing risk signatures, aiming to predict CM prognosis. This evidence concerns the gene CCDC18 and cutaneous mastocytosis.