METTL14 and neoplasm: Furthermore, METTL14/ALKBH5 formed a complex with HuR to maintain its stability and promoted tumor progression by regulating the cell cycle and TGFβ signaling–associated transcripts.[86] These findings suggest that maintaining m6A modification at optional levels is crucial for human health and provide a novel sight for m6A the writers-erasers-readers axis in the CRC.