Our study also showed that low NT-proBNP levels had a lower risk of all-cause death or heart transplantation in non-atrial fibrillation and younger patients, and the cutoff values of NT-proBNP in atrial fibrillation and older patients were higher than those in non-atrial fibrillation and younger patients (Fig. S1A and B, Supplemental Digital Content, http://links.lww.com/MD/K890), which may be associated with the lower risk of adverse events in non-atrial fibrillation and younger patients. Here, NPPB is linked to atrial fibrillation.